AB0325 FREQUENCY OF ATHEROMATOUS PLAQUES IN CAROTID ARTERIES BY DOPPLER IN PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS, SANTO DOMINGO, DOMINICAN REPUBLIC

Background: Systemic lupus erythematosus (SLE) is a multisystemic autoimmune disease. 1 Atherosclerosis considered an alteration of the arteries by abnormal deposit lipids and fibrous tissue. 2 Cardiovascular disease one leading causes morbidity mortality, especially due to its precocity, which occurs in women during childbearing age, associated with higher prevalence cardiovascular (CVD), accelerated atherosclerosis 3,4,5 . Patients rheumatic diseases have increased risk systemic inflammation endothelial dysfunction, promotes 2. Objectives: Evaluate frequency atheromatous plaques patients erythematosus. Methods: Observational, prospective, cross-sectional study. Carotid Doppler was performed on SLE from external consultation rheumatology service November 2019 2020. Inclusion criteria: > 18 years old, diagnosis classification criteria ACR 2007, realization Doppler. Controls: no disease, equated age sex. The data analyzed SPSS V23. Results: 116 met inclusion criteria, including female controls. Mean sick time 6.23 years. 14.65% (17) had atheromaus plates, 29.4% calcified plates (5). 34.7% Dyslipidemia (63.1%) (73), obesity (33), high blood pressure 23.1% (22), diabetes 3.44% (4), smokers 0% (0). activity rate using SLEDAI showed 68.96% (80) without activity, 13.79% (16) low, 11.20% (13) moderate, 6.03% (7) activity. About control group (116), 19.82% (23) 39.13% (9) plates. Conclusion: Our study shows that less than quarter carotid In relation LES vast majority are low We suggest for evaluation monitoring risk. there atheroma plaque formation patients, compared general population. References: [1]Hernández Muñiz, Y., Guibert Toledano, Z. Reyes Llerena, G., 2015. Correlation C Reactive Protein Figures Lupus Erythematosus. [2]Saldarriaga Rivera, L., Ventura Ríos, Hernández Díaz, C. Pineda Villaseñor, C., 2016. Measurement thickness intimate-half carotid: utility ultrasound subcline diseases. Literature review. Rev Col Reum, 23(2), pp.92-101. [3]Telles, R., Lanna, Ferreira, Souza, A., Navarro, T. Ribeiro, 2008. atherosclerotic alterations treated at Brazilian university setting. Lupus, 17(2), pp.105-113. [4]Nienhuis, H., Leeuw, K., Bijzet, J., van Doormaal, Roon, Smit, Graaff, Kallenberg, Bijl, M., 2010. Small artery elasticity decreased intima media thickness. Arthritis Research & Therapy , 12(5), p.R181. [5]Frerix et al. 2014, 16: R54. [6]Marta, Joan T., Stefano B., Chapt - Assessment Disease Activity Erythematosus, Mosby, 2007. Disclosure Interests: None declared